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Fourier Transform Mass Spectrometry (FT-ICR and Orbitrap) for the study of small molecules.

The last two decades have led to the widespread availability of Fourier Transform Mass Spectrometry (FTMS) for many researchers in France, through the acquisition of this type of equipment or through projects carried out thanks to the INC's Infranalytics research infrastructure (FR2054). Ion cyclotron resonance (FT-ICR) and Orbitrap instruments achieve very high mass resolution (105 to 106) and unparalleled mass measurement accuracy (error < 1 ppm). The combinations with various separation techniques and the various ionization sources associated with it make FT-MS an incomparable tool for the qualitative and quantitative study of complex media involving several hundred to several thousand small molecules (50 to 1,500 Da) in the fields of energy, the environment, biology, archaeology, and cosmology. However, FTMS techniques still require significant expertise in both the data acquisition and processing phases.

Part of the CNRS training programs, the FTMS 2025 school is free for CNRS staff and is also widely open to doctoral students, postdoctoral fellows, engineers, researchers, and lecturers (the number of participants is limited to 40). Organized from May 19 to 23 in Moselle on the VVF site "Les Vosges Bitche" by the Infranalytics research infrastructure and the MassLor platform of the LCP-A2MC, the school aims to provide theoretical and practical training. It will allow participants to understand new technological advances, better target the contributions of FTMS in the context of their research projects and provide the tools necessary for the interpretation of the large quantities of data generated. It will also promote exchanges with experts in the field on issues related to their research theme.