News
Identification of potential aggregation sites on Aβ42 fibrils, blocked by the anti-amyloid chaperone type BRICHOS domain.
High-field MAS NMR allows the identification of potential autocatalytic sites on the surface of Aβ42 fibrils.
Monitoring interactions between antibiotics and their targets within bacterial cells by in cell nuclear magnetic resonance (NMR) spectroscopy.
In this research work, our team explored the possibility of using nuclear magnetic resonance (NMR) in cell, that is to say directly on bacterial cell cultures, to characterize the bacterial periplasm, a front-line cellular compartment. of the action of antibiotics. The objective was to follow the fate of these antibiotics in this compartment, in the presence or absence of the expression by the bacteria of β-lactamase enzymes linked to bacterial resistance. This study shows that in cell NMR constitutes a powerful analytical tool for the study of new molecules targeting the molecular components of the bacterial periplasm.
Structural basis on the interaction of two Staphylococcus aureus enzymes with the bacterial envelope
Towards understanding the bacterial wall of staphylococci aureus...
The coupling between FT-ICR and separation techniques is the subject of a new review
A review recently published by the MassLor-LCP-A2MC-UL site
Inauguration of the 1,2 GHz NMR spectrometer on January 4, 2023 at the Lille site
Inauguration of the 1.2 GHz spectrometer
Older posts
- Acceptance and commissioning of the INFRANALYTICS 1,2 GHz NMR spectrometer on the Lille site19th October, 2022
- A new ERC and an ERC "proof of concept" extension grant at CRMN Lyon.July 19, 2022
- Paramagnetic NMR under rotation at the magic angle applied to quadrupole nuclei. A study of sodium-ion battery materialsJuly 04, 2022
- Arrival of a very high-speed 4-channel HFXY NMR MAS probe in OrléansJuly 01, 2022
- How does a supramolecular gel cause cancer cells to die?18th May 2022
- RPE Spin trap to study the catalytic degradation of organic pollutants present in wastewaterMarch 03, 2022
- An oligomeric complex formed during meiosis studied by structural biologyMarch 03, 2022
- Identification through NMR screening of a SARS-CoV-2 protease inhibitorMarch 03, 2022
- Metabolite-protein interactions in biological fluidsMarch 03, 2022
- Creation of the 200th LabComMarch 03, 2022
- MassLor-LCP-A2MC-UL23th February 2022
- MSAP, CNRS/University of Lille23th February 2022
- LASIRE, CNRS/University of Lille23th February 2022
- Institute of Physical Chemistry - CNRS/Paris Saclay University23th February 2022
- IPCM, CNRS/Sorbonne University23th February 2022
- CEMHTI Orleans23th October, 2013