Recently, CNRS chemists and paleontologists managed to identify an animal from a milligram of bone.

This work was carried out on the platform Lille FTICR MSAP and published in Anal Chem in 2023. This collaboration between the Miniaturization for Synthesis, Analysis and Proteomics laboratory (CNRS/University of Lille), the Evolution, Ecology and Paleontology laboratory (CNRS/University of Lille) and the laboratory of Physical Geography: Quaternary and Current Environments (CNRS/Panthéon-Sorbonne University/Paris-Est Créteil Val-de-Marne University) has brought together the expertise and state-of-the-art equipment necessary for this advance in paleoproteomics. For each bone (around XNUMX), one milligram of material was powdered, washed and digested with an enzyme to recover the peptides. Once the samples were purified, they were analyzed by MALDI-FTICR.

 DSC03135 3a9cf

To find out more: 

https://www.inc.cnrs.fr/fr/cnrsinfo/chimie-archeologie-et-paleontologie-un-milligramme-dos-suffit

https://doi.org/10.1021/acs.analchem.2c03301